Primary Identifier | MGI:1341264 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 21983 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including dendrite arborization; olfactory learning; and positive regulation of intracellular signal transduction. Located in several cellular components, including axon terminus; dendrite; and endoplasmic reticulum. Is expressed in several structures, including brain; epithelium; extraembryonic component; skin; and urinary system. Orthologous to human TPBG (trophoblast glycoprotein). PHENOTYPE: Mice homozygous for a knock-out allele exhibit low penetrance hydrocephaly and premature death. Embryonic stem cells isolated from these mice exhibit impaired mesenchyme differentiation and reduced chemotaxis following differentiation. [provided by MGI curators] |