| Primary Identifier | MGI:2685968 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 382089 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in somite rostral/caudal axis specification. Acts upstream of or within several processes, including Notch signaling pathway; determination of left/right symmetry; and post-anal tail morphogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in embryo mesoderm; paraxial mesenchyme; and tail bud. Used to study spondylocostal dysostosis. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 6. Orthologous to human RIPPLY2 (ripply transcriptional repressor 2). PHENOTYPE: Mice homozygous for null mutations display neonatal lethality, rib and vertebral abnormalities, impaired somite formation, decreased body length, and short tails. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
