| Primary Identifier | MGI:1340032 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 107885 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 5-formyltetrahydrofolate cyclo-ligase activity; double-stranded DNA binding activity; and heterocyclic compound binding activity. Predicted to be involved in folic acid-containing compound biosynthetic process and tetrahydrofolate interconversion. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to several human genes including MTHFS (methenyltetrahydrofolate synthetase). PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Heterozygous mice display decreased de novo purine synthesis and reduced plasma folate levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
