Primary Identifier | MGI:1929897 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 64085 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity. Involved in associative learning and inhibitory synapse assembly. Acts upstream of or within positive regulation of synapse assembly and positive regulation of synaptic transmission. Located in cell surface; postsynaptic density; and postsynaptic membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including brain; ear; forelimb bud; heart; and paraxial mesenchyme. Orthologous to human CLSTN2 (calsyntenin 2). PHENOTYPE: Homozygous KO mice display deficiency in spatial learning and memory in Morris water and Barnes maze tasks and increased locomotor activity in open field test. [provided by MGI curators] |