Primary Identifier | MGI:1921330 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 74080 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nicotinamide-nucleotide adenylyltransferase activity. Acts upstream of or within NAD biosynthetic process and response to wounding. Located in mitochondrion. Is expressed in several structures, including alimentary system; hemolymphoid system; liver; retina; and urinary system. Orthologous to human NMNAT3 (nicotinamide nucleotide adenylyltransferase 3). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit splenomegaly and hemolytic anemia resulting from a glycolysis pathway blockade. [provided by MGI curators] |