| Primary Identifier | MGI:1344387 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 23873 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in cytoplasm. Is expressed in several structures, including gonad; hemolymphoid system; intestine; liver; and retina. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). PHENOTYPE: Mice homozygous for a null allele have thymocytes with an enhanced susceptibility to FAS-induced apoptosis, and B cells that more susceptible to activation induced cell death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
