Primary Identifier | MGI:2143261 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 333424 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables acetylglucosaminyltransferase activity. Acts upstream of or within negative regulation of epithelial cell proliferation and protein O-linked glycosylation. Predicted to be located in Golgi membrane. Orthologous to human A4GNT (alpha-1,4-N-acetylglucosaminyltransferase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit gastric adenocarcinoma with increased cell proliferation, angiogenesis, inflammation and gastric mucosal thickness. [provided by MGI curators] |