| Primary Identifier | MGI:2143266 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 213208 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables interleukin-20 binding activity. Acts upstream of or within several processes, including CD8-positive, alpha-beta T cell homeostasis; negative regulation of type IV hypersensitivity; and regulation of cytokine production. Predicted to be active in plasma membrane. Is expressed in foregut; male reproductive gland or organ; metanephros; skin; and thymus. Orthologous to human IL20RB (interleukin 20 receptor subunit beta). PHENOTYPE: Mice homozygous for a knock-out allele display enhanced antigen-specific T cell responses. Mice homozygous for a reporter allele fail to exhibit epidermal hyperplasia in an interleukin-23 (IL-23)-dependent psoriasis mouse model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
