Primary Identifier | MGI:1098658 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 20842 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Predicted to be involved in mitotic spindle assembly and sister chromatid cohesion. Located in chromatin. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 47. Orthologous to human STAG1 (STAG1 cohesin complex component). PHENOTYPE: Mouse embryos homozygous for a null mutation show developmental delay and die before birth. Heterozygous animals have shorter lifespan and earlier onset of tumourigenesis. [provided by MGI curators] |