Primary Identifier | MGI:87989 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 11655 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 5-aminolevulinate synthase activity. Involved in heme A biosynthetic process; heme B biosynthetic process; and heme O biosynthetic process. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in several structures, including adrenal gland; alimentary system; liver; and male reproductive system. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1). PHENOTYPE: Mice homozygous for a reporter allele exhibit embryonic lethality. [provided by MGI curators] |