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Protein Coding Gene : Alas1 aminolevulinic acid synthase 1

Primary Identifier  MGI:87989 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  11655
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables 5-aminolevulinate synthase activity. Involved in heme A biosynthetic process; heme B biosynthetic process; and heme O biosynthetic process. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in several structures, including adrenal gland; alimentary system; liver; and male reproductive system. Orthologous to human ALAS1 (5'-aminolevulinate synthase 1).
PHENOTYPE: Mice homozygous for a reporter allele exhibit embryonic lethality. [provided by MGI curators]
  • synonyms:
  • succinyl-CoA: glycine C-succinyl transferase,
  • ALAS-N,
  • MGD-MRK-1268,
  • Alas-1,
  • aminolevulinic acid synthase 1,
  • 5-aminolevulinate synthase,
  • MGD-MRK-1270,
  • Alas1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For