Primary Identifier | MGI:1890471 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 59092 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA 3'-UTR binding activity. Acts upstream of or within negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and negative regulation of mRNA splicing, via spliceosome. Predicted to be located in cytosol. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; dorsal root ganglion; lung; metanephros; and sensory organ. Orthologous to human PCBP4 (poly(rC) binding protein 4). PHENOTYPE: Mice homozygous or heterozygous for a knock-out allele are reduced in body weight and prone to lung adenocarcinoma, B cell derived lymphoma and lung tumors. [provided by MGI curators] |