Primary Identifier | MGI:1921517 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 74267 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calmodulin binding activity. Involved in positive regulation of acrosome reaction and positive regulation of flagellated sperm motility involved in capacitation. Located in acrosomal vesicle. Orthologous to human IQCF1 (IQ motif containing F1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility associated with decreased sperm motility and impaired induced acrosome reaction. [provided by MGI curators] |