Primary Identifier | MGI:2445220 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 321006 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone H2AT120 kinase activity; nuclear estrogen receptor binding activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in B cell differentiation and V(D)J recombination. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of COP9 signalosome and Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in centrosome and nucleus. Orthologous to human DCAF1 (DDB1 and CUL4 associated factor 1). PHENOTYPE: Embryos homozygous for a knock-out allele die prior to E7.5. [provided by MGI curators] |