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Protein Coding Gene : Sema3b sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

Primary Identifier  MGI:107561 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  20347
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. Is expressed in several structures, including genitourinary system; gut mucosa; nervous system; skeletal musculature; and tooth. Orthologous to human SEMA3B (semaphorin 3B).
PHENOTYPE: Mice homozygous for one knock-out allele are viable and fertile with no obvious pathological abnormalities. Mice homozygous for a second knock-out allele exhibit improper positioning of a major brain commissural projection, the anterior commissure. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW208495,
  • MGI:2143295,
  • MGD-MRK-36132,
  • Semaa,
  • LUCA-1,
  • semaV,
  • SemA,
  • AW208495,
  • sema5,
  • semaphorin A,
  • Sema3b,
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

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