Primary Identifier | MGI:107561 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 20347 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. Is expressed in several structures, including genitourinary system; gut mucosa; nervous system; skeletal musculature; and tooth. Orthologous to human SEMA3B (semaphorin 3B). PHENOTYPE: Mice homozygous for one knock-out allele are viable and fertile with no obvious pathological abnormalities. Mice homozygous for a second knock-out allele exhibit improper positioning of a major brain commissural projection, the anterior commissure. [provided by MGI curators] |