| Primary Identifier | MGI:1923750 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 76500 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables inositol hexakisphosphate kinase activity. Involved in inositol phosphate biosynthetic process. Acts upstream of or within positive regulation of peptidyl-serine phosphorylation and protein stabilization. Located in nucleus. Is expressed in several structures, including alimentary system; heart; nervous system; respiratory system; and sensory organ. Orthologous to human IP6K2 (inositol hexakisphosphate kinase 2). PHENOTYPE: Homozygotes for a null allele are resistant to radiation-induced mortality and show increased double-strand DNA break repair and incidence of induced aerodigestive tract carcinomas. Homozygotes for another null allele show increased B cell viability after radiation or neocarzinostatin treatment. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
