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Protein Coding Gene : Cspg5 chondroitin sulfate proteoglycan 5
Primary Identifier  MGI:1352747 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  29873
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within modulation of chemical synaptic transmission. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Is expressed in central nervous system; enteric nervous system; and retina. Orthologous to human CSPG5 (chondroitin sulfate proteoglycan 5).
PHENOTYPE: Homozygous null mice display decreased spontaneous postsynaptic currents, increased paired-pulse ratios, and reduced long term depression during early postnatal developmental stages. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI604859,
  • MGI:2143104,
  • AI604859,
  • neuroglycan C,
  • NGC,
  • Cspg5,
  • CALEB,
  • chondroitin sulfate proteoglycan 5
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Phenotype

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Disease

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