Primary Identifier | MGI:2143315 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 270201 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in protein ubiquitination. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in nervous system and retina nuclear layer. Orthologous to human KLHL18 (kelch like family member 18). PHENOTYPE: Mice homozygous for a null allele exhibit progressive increase in auditory brain stem response with tapered inner hair cell stereocilia. [provided by MGI curators] |