Primary Identifier | MGI:1098237 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 16578 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP hydrolysis activity; identical protein binding activity; and microtubule binding activity. Involved in regulation of flagellated sperm motility. Located in sperm flagellum. Is expressed in cochlea; hippocampus; lateral ventricle choroid plexus; metanephros; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human KIF9 (kinesin family member 9). PHENOTYPE: Homozygous inactivation of this gene leads to reduced male fertility and asthenozoospermia associated with asymmetric flagellar waveform patterns and decreased sperm progressive motility. [provided by MGI curators] |