| Primary Identifier | MGI:1923749 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 76499 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule binding activity. Involved in cell migration and establishment of cell polarity. Acts upstream of or within establishment or maintenance of cell polarity; fibroblast migration; and negative regulation of microtubule depolymerization. Located in Golgi apparatus; cell leading edge; and microtubule. Is expressed in central nervous system; dorsal root ganglion; early conceptus; oocyte; and trigeminal nerve. Orthologous to human CLASP2 (cytoplasmic linker associated protein 2). PHENOTYPE: Targeted deletion of this gene leads to impaired formation of stable microtubules in a wound healing assay, and results in a 2-fold reduction of directionally persistent migration in mutant embryonic fibroblasts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
