Primary Identifier | MGI:2135610 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235661 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GDP binding activity; dynein heavy chain binding activity; and identical protein binding activity. Predicted to be involved in several processes, including cellular response to nerve growth factor stimulus; early endosome to recycling endosome transport; and regulation of cell cycle process. Predicted to be located in cytoplasmic vesicle; kinetochore; and spindle pole. Predicted to be part of cytoplasmic dynein complex. Predicted to colocalize with centrosome. Orthologous to human DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit increased anxiety-related response, increased dendrite length, increased neuron migration, and decreased lysosome trafficking. [provided by MGI curators] |