Primary Identifier | MGI:2447166 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 102545 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity. Acts upstream of or within B-1a B cell differentiation. Predicted to be located in extracellular space. Predicted to be active in membrane. Is expressed in thymus primordium. Orthologous to human CMTM7 (CKLF like MARVEL transmembrane domain containing 7). PHENOTYPE: Heterozygous mice die shortly after birth. Null mutations in this gene are haploinsufficient. A chimeric mouse showed defects in B-1a cell numbers and physiology. [provided by MGI curators] |