| Primary Identifier | MGI:1351332 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 27215 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in negative regulation of canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including T cell activation; dendritic cell differentiation; and dendritic cell proliferation. Located in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human AZI2 (5-azacytidine induced 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired GM-CSF-derived bone marrow-derived dendritic cell differenatiation, cytokine response and ability to stimulate T cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
