| Primary Identifier | MGI:1201683 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 13813 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and chromatin DNA binding activity. Involved in several processes, including gastrulation; nervous system development; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including endodermal cell fate specification; nervous system development; and trophectodermal cell differentiation. Located in chromatin and nucleus. Is expressed in several structures, including brain; early conceptus; gonad; limb; and limb bud. Orthologous to human EOMES (eomesodermin). PHENOTYPE: Homozygous null mice display embryonic lethality, fail to implant, and lack trophoectoderm outgrowth. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
