Primary Identifier | MGI:1921748 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 74498 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Involved in Golgi ribbon formation. Acts upstream of or within Golgi organization and protein N-linked glycosylation. Located in Golgi apparatus. Is expressed in cortical layer V and hippocampus CA1. Orthologous to human GORASP1 (golgi reassembly stacking protein 1). PHENOTYPE: Mice homozygous for a targeted disruption of this gene are viable, fertile and healthy with no detectable tissue defects. However, immortalized mutant embryonic fibroblasts show loss of cis Golgi integrity and glycosylation defects. [provided by MGI curators] |