Primary Identifier | MGI:1921302 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 74052 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in flagellated sperm motility and spermatid development. Predicted to be part of intraciliary transport particle A. Is expressed in 4th ventricle; choroid plexus; lateral ventricle choroid plexus; and olfactory epithelium. Human ortholog(s) of this gene implicated in spermatogenic failure 37. Orthologous to human TTC21A (tetratricopeptide repeat domain 21A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility and asthenoteratospermia characterized by reduced sperm motility and multiple sperm malformations affecting the flagella and the connecting piece. [provided by MGI curators] |