| Primary Identifier | MGI:1333878 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 22437 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity and filamin binding activity. Involved in myoblast differentiation involved in skeletal muscle regeneration; protein localization; and satellite cell activation involved in skeletal muscle regeneration. Acts upstream of or within several processes, including Notch signaling pathway; negative regulation of cell population proliferation; and striated muscle cell development. Located in adherens junction and fascia adherens. Is expressed in several structures, including heart; musculature; and tail somite. Used to study hypertrophic cardiomyopathy. Orthologous to human XIRP1 (xin actin binding repeat containing 1). PHENOTYPE: Homozygous mice exhibit cardiac hypertrophy and a disruption of cardiac intercalated disc structure and myofilament abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
