Primary Identifier | MGI:88297 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 12424 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neuropeptide hormone activity. Involved in cholecystokinin signaling pathway. Acts upstream of or within axonogenesis; eating behavior; and neuron migration. Located in axon. Is expressed in several structures, including alimentary system; eye; genitourinary system; immune system; and nervous system. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human CCK (cholecystokinin). PHENOTYPE: Homozygous mice for one allele exhibit a significant decrease in prepulse inhibition while mice for another mutation appear normal but have increased enzyme levels of pancreatic amylase. [provided by MGI curators] |