Primary Identifier | MGI:1891697 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 59289 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables C-C chemokine binding activity and C-C chemokine receptor activity. Acts upstream of or within signal transduction. Predicted to be located in several cellular components, including actin filament; cytosol; and nucleus. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and trophoblast giant cell. Orthologous to human ACKR2 (atypical chemokine receptor 2). PHENOTYPE: Homozygous null mice display increased inflammatory responses but are viable and fertile without any other gross abnormalities. [provided by MGI curators] |