Primary Identifier | MGI:1934582 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 80901 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables C-X-C chemokine binding activity and C-X-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR6 (C-X-C motif chemokine receptor 6). PHENOTYPE: A small percentage of mice that are heterozygous or homozygous for a knock-out allele develop medulloblastomas in the cerebellum after 12 months of age. [provided by MGI curators] |