Primary Identifier | MGI:1346338 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 23832 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Acts upstream of or within chemotaxis; release of sequestered calcium ion into cytosol; and response to cytokine. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; immune system; intestine; and reproductive system. Orthologous to human XCR1 (X-C motif chemokine receptor 1). PHENOTYPE: Mice homozygous for a targeted null mutation exhibit reduced CD8+ dendritic cell migration in response to XCL1. [provided by MGI curators] |