Primary Identifier | MGI:2147968 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 102991 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone methyltransferase inhibitor activity. Acts upstream of or within chromatin organization and oocyte development. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in axial skeleton and rib. Orthologous to human EZHIP (EZH inhibitory protein). PHENOTYPE: Females homozygous for a null allele show reduced fertility, with fewer and smaller litters, smaller ovaries, and reduced primordial follicle number. Males exhibit normal fertility. [provided by MGI curators] |