Primary Identifier | MGI:2183443 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 209091 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be located in nuclear speck. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in germ cell of ovary; germ cell of testis; ovary; seminiferous tubule; and testis. Orthologous to human CCNB3 (cyclin B3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal female meiosis and female infertility whereas hemizygous males are fertile. Most mutant oocytes fail to progress beyond metaphase I. [provided by MGI curators] |