Primary Identifier | MGI:102794 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 11643 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase A binding activity. Involved in flagellated sperm motility and spermatogenesis. Acts upstream of or within several processes, including cell surface receptor protein serine/threonine kinase signaling pathway; establishment of protein localization; and sperm flagellum assembly. Located in Z disc; perinuclear region of cytoplasm; and sperm flagellum. Orthologous to human AKAP4 (A-kinase anchoring protein 4). PHENOTYPE: Inactivation of this locus results in male infertility due to impaired sperm motility. Heterozygous mutant females show no reproductive defects. [provided by MGI curators] |