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Protein Coding Gene : Gripap1 GRIP1 associated protein 1
Primary Identifier  MGI:1859616 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  54645
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable guanyl-nucleotide exchange factor activity; identical protein binding activity; and ionotropic glutamate receptor binding activity. Involved in regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in heart; lung; nervous system; and sensory organ. Orthologous to human GRIPAP1 (GRIP1 associated protein 1).
PHENOTYPE: Homozygous knockout affects long term potentiation in hippocampal neurons resulting in impaired spatial and associative learning and memory. [provided by MGI curators]
  • synonyms:
  • Sfc10,
  • DNA segment, Chr X, Immunex 47, expressed,
  • Gripap1,
  • expressed sequence AI854681,
  • GRIP1 associated protein 1,
  • DXImx47e,
  • AI854681,
  • GRASP-1,
  • MGI:2147934
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