Primary Identifier | MGI:1353431 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 30052 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within peptide hormone processing; response to cold; and response to dietary excess. Located in extracellular space; secretory granule; and trans-Golgi network. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor). PHENOTYPE: Mice homozygous for a null allele have behavioral/neurological defects as well as decreased body weight. [provided by MGI curators] |