| Primary Identifier | MGI:1099440 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 20937 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and histone H3K9me2 methyltransferase activity. Involved in circadian rhythm; negative regulation of DNA-templated transcription; and negative regulation of gene expression, epigenetic. Acts upstream of or within several processes, including blastocyst hatching; determination of adult lifespan; and regulation of bone mineralization. Located in heterochromatin and nucleus. Part of chromatin silencing complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human SUV39H1 (SUV39H1 histone lysine methyltransferase). PHENOTYPE: About one third of mice either heterozygous or homozygous for a reporter/null allele develop late-onset B cell lymphomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
