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Protein Coding Gene : Tbc1d25 TBC1 domain family, member 25
Primary Identifier  MGI:2444862 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  209815
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of autophagosome maturation. Predicted to be located in cytoplasmic vesicle. Predicted to be active in autophagosome. Orthologous to human TBC1D25 (TBC1 domain family member 25).
PHENOTYPE: Male mice hemizygous for a knock-out allele show exacerbated cardiac hypertrophy, fibrosis and dysfunction in response to partial transverse aortic constriction. [provided by MGI curators]
  • synonyms:
  • 6330576A08Rik,
  • DNA segment, Chr X, human S7927E, expressed,
  • DXHXS7927e,
  • ornithine aminotransferase-like 1,
  • MGI:1099472,
  • RIKEN cDNA 6330576A08 gene,
  • Tbc1d25,
  • mMg81,
  • Oatl1,
  • TBC1 domain family, member 25
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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Disease

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