| Primary Identifier | MGI:2148066 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 209837 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables L-glutamine, sodium:proton antiporter activity. Involved in L-glutamine import across plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; foregut-midgut junction; liver lobe; metanephros; and pericardium. Orthologous to human SLC38A5 (solute carrier family 38 member 5). PHENOTYPE: The gene product plays a role in mediating amino-acid-stimulated pancreatic alpha cell proliferation. Under glucagon receptor (Gcgr) inhibition conditions, homozygous KO reduces alpha cell hyperplasia and causes hypoglycemia and increased plasma glucagon and amino acid levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
