| Primary Identifier | MGI:1923224 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 75974 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including marginal zone B cell differentiation; positive regulation of GTPase activity; and positive regulation of filopodium assembly. Is expressed in brain; female reproductive system; gut; skin; and spleen. Orthologous to human DOCK11 (dedicator of cytokinesis 11). PHENOTYPE: Homozygous knockout leads to the reduction of the number of B cells in the spleen marginal zone and the increase in thymic CD4+ T cell percentage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
