| Primary Identifier | MGI:105052 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 16164 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine binding activity and interleukin-13 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and positive regulation of immunoglobulin production. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including aorta; brain; gut; liver; and lung. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human IL13RA1 (interleukin 13 receptor subunit alpha 1). PHENOTYPE: Mice homozygous for a null allele exhibit enhanced Th2 response, decreased susceptibility to parasitic infection and decreased airway hyperreactivity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
