Primary Identifier | MGI:1927290 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 56805 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and methyl-CpG binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to act upstream of or within DNA-templated transcription. Located in nucleus. Is expressed in several structures, including bladder; central nervous system; early conceptus; eye; and gonad. Orthologous to human ZBTB33 (zinc finger and BTB domain containing 33). PHENOTYPE: Homozygous null females and hemizygous null males are viable, fertile and overtly normal with no detectable changes in blood cell composition. [provided by MGI curators] |