| Primary Identifier | MGI:2442413 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 331401 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA binding activity. Acts upstream of or within several processes, including blastocyst development; regulation of mRNA export from nucleus; and stem cell division. Located in nucleus. Is expressed in early conceptus and inner cell mass. Used to study X-linked intellectual disability-short stature-overweight syndrome. Human ortholog(s) of this gene implicated in X-linked intellectual disability-short stature-overweight syndrome. Orthologous to human THOC2 (THO complex subunit 2). PHENOTYPE: Male mice hemizygous for a hypomorphic allele display partial lethality before implantation, decreased body and organ size and weight, learning and fine motor coordination deficits, and neurological abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
