| Primary Identifier | MGI:107572 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 11798 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enzyme binding activity; and scaffold protein binding activity. Involved in regulation of apoptosis involved in tissue homeostasis and response to lipopolysaccharide. Acts upstream of or within negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity; and neuron apoptotic process. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to several human genes including XIAP (X-linked inhibitor of apoptosis). PHENOTYPE: Homozygous null mutants are indistinguishable from normal littermates, but increased levels of protein from other Birc gene family members suggest a compensatory mechanism in the absence of the Birc4 gene's product. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
