Primary Identifier | MGI:1920610 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 73360 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of smoothened signaling pathway. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in actin cytoskeleton and nucleus. Orthologous to human ACTRT1 (actin related protein T1). PHENOTYPE: Knock-out males show severely impaired fertility, with 60% acephalic spermatozoa and defects in sperm head-tail coupling apparatus. [provided by MGI curators] |