Primary Identifier | MGI:1935127 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 93761 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Involved in neuron differentiation. Acts upstream of or within brain development and regulation of neural precursor cell proliferation. Located in chromatin. Part of CERF complex. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SMARCA1 (SNF2 related chromatin remodeling ATPase 1). PHENOTYPE: Female mice homozygous and male mice hemizygous for a targeted disruption of this gene exhibit abnormalities in neuron differentiation and neuronal precursor proliferation, increased brain and heart weight, and forebrain hypercellularity. [provided by MGI curators] |