| Primary Identifier | MGI:1921381 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 74131 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including positive regulation of gene expression; positive regulation of lymphocyte activation; and positive regulation of organ growth. Located in cytoplasm and nucleus. Is expressed in heart ventricle and thymus primordium. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human SASH3 (SAM and SH3 domain containing 3). PHENOTYPE: Mice homozygous for a truncation allele exhibit decreased T and B cells, altered B cell physiology and increased length of semi-identical allograft survival. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
