| Primary Identifier | MGI:2147913 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 209268 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable activin receptor antagonist activity; coreceptor activity; and inhibin binding activity. Predicted to be involved in immune response-regulating signaling pathway; negative regulation of activin receptor signaling pathway; and regulation of DNA-templated transcription. Predicted to be located in extracellular region. Predicted to be active in membrane. Is expressed in several structures, including forebrain; liver; and medulla oblongata part of 4th ventricle choroid plexus. Used to study IGSF1 deficiency syndrome. Human ortholog(s) of this gene implicated in IGSF1 deficiency syndrome. Orthologous to human IGSF1 (immunoglobulin superfamily member 1). PHENOTYPE: Females homozygous for disruptions of this gene show no obvious phenotypic change. Hemizygous males show hypothyroidism and increased body weight. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
