| Primary Identifier | MGI:98888 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 22187 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within several processes, including fat pad development; gonad development; and meiosis I. Located in myelin sheath. Is expressed in several structures, including adrenal gland; gonad; intestine; liver; and lung. Orthologous to human UBB (ubiquitin B). PHENOTYPE: Targeted disruption of this gene results in progressive degeneration of hypothalamic neurons accompanied by impaired hypothalamic control of energy balance and adult-onset obesity. Both genders are infertile due to a failure of germ cells to progress through meiosis I and hypogonadism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
