| Primary Identifier | MGI:2685210 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245423 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including positive regulation of Notch signaling pathway; positive regulation of protein modification process; and protein localization to plasma membrane. Located in plasma membrane. PHENOTYPE: Mice homozygous for a knock-out allele show reduced female fertility, decreased numbers of primordial and growing ovarian follicles, and impaired oocyte quality associated with oxidative stress, decreased mitochondrial membrane potential, decreased oocyte maturation, and increased aneuploidy. [provided by MGI curators] |