Primary Identifier | MGI:2442509 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 245446 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within axonogenesis and positive regulation of synapse assembly. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse. Is expressed in several structures, including brain; ganglia; and spinal cord. Orthologous to human SLITRK4 (SLIT and NTRK like family member 4). PHENOTYPE: Hemizygous null male mice display enhanced fear memory acquisition, reduced social investigation, enhanced long-term potentiation, and abnormalities in interneurons in the amygdala. [provided by MGI curators] |